Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337535 | 0.80 | L3MBTL1 (0.47) | L3MBTL1ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1339803 | 0.79 | L3MBTL1 (0.46) | L3MBTL1ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1339754 | 0.79 | MEN1 (0.73) | L3MBTL1ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10940030 | 0.76 | MEN1 (0.69) | L3MBTL1ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1340375 | 0.74 | LMNA (0.55) | L3MBTL1ATMNPC1LMNATP53 | |
| SCHEMBL1337759 | 0.74 | CCR8 (0.60) | — | |
| SCHEMBL3690385 | 0.73 | HPGD (0.77) | L3MBTL1ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1339604 | 0.73 | CCR8 (0.60) | MEN1KMT2A | |
| SCHEMBL24448306 | 0.70 | RAB9A (0.63) | L3MBTL1ALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL13581610 | 0.70 | MAPT (0.71) | L3MBTL1ALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378525-B2 | CCR8 inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-05-27 | — | — | US | disclosed |