Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189060 | 0.84 | GRIK1 (0.47) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL14215793 | 0.82 | FABP4 (0.61) | MAPTAKR1C3AKR1C2RXFP1MT-CO2 | |
| SCHEMBL14632251 | 0.79 | DHODH (0.47) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL14215824 | 0.78 | KMT2A (0.60) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL14392041 | 0.72 | AKR1C3 (0.51) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL14189063 | 0.72 | AKR1C3 (0.44) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL29773126 | 0.71 | TSHR (0.55) | MAPTGFERNGLY1CYP3A4TSHR | |
| SCHEMBL3109673 | 0.71 | CES2 (0.59) | MAPTGFERCYP3A4TSHRALOX15 | |
| SCHEMBL28978590 | 0.71 | MPO (0.67) | MAPTGFERNGLY1AKR1C3AKR1C2 | |
| SCHEMBL23682948 | 0.70 | AKR1C3 (0.49) | MAPTGFERNGLY1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378154-B2 | Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes | DAIKIN INDUSTRIES, LTD. (JP) | 2008-05-27 | — | — | US | disclosed |