Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480246 | 0.79 | KAT6A (0.38) | ESR1ESR2PTGS1ALDH1A1EPAS1 | |
| SCHEMBL14215943 | 0.77 | PDK2 (0.44) | ESR1ESR2PTGS1ALDH1A1HSP90AA1 | |
| SCHEMBL14215947 | 0.75 | ESR1 (0.36) | ESR1ESR2PTGS1ALDH1A1PDK2 | |
| SCHEMBL14215938 | 0.75 | CA2 (0.35) | ALDH1A1 | |
| SCHEMBL11420060 | 0.74 | HSD17B10 (0.43) | ESR1ESR2PDK1PDK2PDK3 | |
| SCHEMBL9694363 | 0.74 | ALDH1A1 (0.40) | ESR1ESR2ALDH1A1POLBGAA | |
| SCHEMBL7937188 | 0.66 | ALDH1A1 (0.48) | ALDH1A1EPAS1 | |
| SCHEMBL18513448 | 0.65 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1POLBGAA | |
| SCHEMBL517721 | 0.64 | PTPRZ1 (0.53) | ESR1ESR2ALDH1A1GAA | |
| SCHEMBL6264610 | 0.62 | CA2 (0.43) | ALDH1A1POLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378154-B2 | Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes | DAIKIN INDUSTRIES, LTD. (JP) | 2008-05-27 | — | — | US | disclosed |