Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215943 | 0.82 | PDK2 (0.44) | ESR1ESR2PTGS1ALDH1A1POLB | |
| SCHEMBL3480246 | 0.81 | KAT6A (0.38) | ESR1ESR2PTGS1ALDH1A1KIF11 | |
| SCHEMBL11420060 | 0.79 | HSD17B10 (0.43) | ESR1ESR2POLBPDK2VEGFA | |
| SCHEMBL9694363 | 0.79 | ALDH1A1 (0.40) | ESR1ESR2ALDH1A1POLBGAA | |
| SCHEMBL14215944 | 0.75 | ESR1 (0.33) | ESR1ESR2PTGS1ALDH1A1POLB | |
| SCHEMBL945367 | 0.71 | MEN1 (0.40) | ALDH1A1GAAMCL1 | |
| SCHEMBL8999889 | 0.71 | TRPV4 (0.41) | PTGS1ALDH1A1POLBGAAGFER | |
| SCHEMBL14215950 | 0.70 | POLB (0.64) | ALDH1A1POLBGAAGFERTDP1 | |
| SCHEMBL18513448 | 0.69 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1POLBGAA | |
| SCHEMBL14600285 | 0.69 | LMNA (0.41) | PTGS1ALDH1A1HSD17B3KIF11FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378154-B2 | Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes | DAIKIN INDUSTRIES, LTD. (JP) | 2008-05-27 | — | — | US | disclosed |