Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 10/20 | 0.40 |
| ▸ | VEGFA | P15692 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215943 | 0.81 | PDK2 (0.44) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL14215947 | 0.79 | ESR1 (0.36) | HSD17B10PDK2ESR1ESR2EPAS1 | |
| SCHEMBL3480246 | 0.79 | KAT6A (0.38) | ESR1ESR2EPAS1VEGFA | |
| SCHEMBL16556209 | 0.79 | ESR1 (0.38) | ESR1ESR2EPAS1VEGFA | |
| SCHEMBL69469 | 0.78 | HSD17B10 (0.52) | HSD17B10PDK2ESR1ESR2HSD11B1 | |
| SCHEMBL9694363 | 0.78 | ALDH1A1 (0.40) | ESR1ESR2EPAS1MEN1KMT2A | |
| SCHEMBL2788764 | 0.78 | HSD11B1 (0.51) | HSD17B10HSD11B1EPAS1VEGFA | |
| SCHEMBL15880399 | 0.76 | TRPV4 (0.53) | HSD17B10PDK2ESR1ESR2TTR | |
| SCHEMBL1808946 | 0.76 | HSD17B10 (0.50) | HSD17B10PDK2ESR1ESR2TTR | |
| SCHEMBL2789841 | 0.76 | HSD11B1 (0.56) | PDK2HSD11B1EPAS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4195082-A | Combating arthropods with 0-alkyl-0-trifluoromethylsulphonylphenyl-thiono (thiol)-phosphoric acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-25 | — | — | US | disclosed |