SCHEMBL14215977

SCHEMBL14215977

C=C1C(=O)O[C@@H]2[C@H]3C(CO)=CC(=O)C3=C(C)C[C@H](OC(=O)Cc3ccc(O)cc3)[C@@H]12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.48
▸ NPC1 O15118 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HTT P42858 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ MITF O75030 1/20 0.35
▸ PAX8 Q06710 1/20 0.35
▸ CYP19A1 P11511 1/20 0.34
▸ FNTA P49354 1/20 0.33
▸ FNTB P49356 1/20 0.33
▸ PGGT1B P53609 1/20 0.33
▸ PTPN1 P18031 2/20 0.32
▸ PTPN2 P17706 1/20 0.31
▸ GPX4 P36969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29973846 0.89 ALDH1A1 (0.47) ALDH1A1NPC1MAPTHTTRAB9A
SCHEMBL30608789 0.82 ALDH1A1 (0.69) ALDH1A1
SCHEMBL28907163 0.78 CYP19A1 (0.34) ALDH1A1CYP19A1
SCHEMBL25938254 0.67 CYP1A2 (0.56) ALDH1A1
SCHEMBL3031437 0.65 ALDH1A1 (1.00) ALDH1A1CYP19A1
SCHEMBL19036305 0.56 GPX4 (0.71) ALDH1A1NPC1MAPTHTTRAB9A
SCHEMBL19036316 0.55 GPX4 (0.76) ALDH1A1NPC1MAPTHTTRAB9A
SCHEMBL9078420 0.53 CYP19A1 (0.69) ALDH1A1NPC1RAB9AKDM4ECYP19A1
SCHEMBL9078999 0.53 CYP19A1 (0.51) NPC1MAPTRAB9AATMTDP1
SCHEMBL1179218 0.53 CYP4Z1 (0.55) ALDH1A1MAPTKDM4EFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255917-A1 COMPOSITION COMPRISING CHICORY ROOT AND PEA CELL WALL FIBER FOR TREATING BRACHYSPIRA INFECTIONS COSUCRA GROUPE WARCOING S.A. (BE) 2025-08-14 — — US claimed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 — — US claimed
US-12290545-B2 Composition comprising chicory root and pea cell wall fiber for treating Brachyspira infections COSUCRA GROUPE WARCOING S.A. (BE) 2025-05-06 — — US claimed
EP-4512471-A2 ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS Attillaps Holdings (US) 2025-02-26 — — EP claimed
US-20250042765-A1 METHOD FOR TREATING A SURFACE CONTAMINATED WITH PSEUDOMONAS AERUGINOSA IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-02-06 — — US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 — — EP claimed
US-12157677-B2 Method for treating a biologically contaminated surface IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-12-03 — — US claimed
EP-4088724-B1 ACETYLCHOLINESTERASE INHIBITORS FOR THE ORAL TREATMENT OF DERMATOLOGICAL CONDITIONS ATTILLAPS HOLDINGS (US) 2024-10-23 — — EP claimed
US-20240325324-A1 COMPOSITIONS AND METHODS FOR TREATING DRY EYE Genetic Disease Investigators, LLC 2024-10-03 — — US claimed
US-20240018011-A1 METHOD FOR TREATING A BIOLOGICALLY CONTAMINATED SURFACE IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-01-18 — — US claimed
US-11446241-B2 Treatment of ophthalmological conditions with acetylcholinesterase inhibitors ATTILLAPS HOLDINGS INC. (US) 2022-09-20 — — US claimed
US-20220287313-A1 USE OF DRIED CHICORY ROOT TO PROTECT POULTRY AND LIVESTOCK AGAINST ECTOPARASITES OR AS INSECT REPELLANT COSUCRA GROUPE WARCOING S.A. (BE) 2022-09-15 — — US claimed
EP-4048720-A1 MULTILAYER DISSOLVABLE SOLID ARTICLE CONTAINING COATING COMPOSITION AND PROCESS FOR MAKING THE SAME The Procter & Gamble Company (US) 2022-08-31 — — EP claimed
EP-4031182-A1 ENDOCANNABINOID MIMETIC AND ANTI-INFLAMMATORY COMPOUND CONTAINING COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF Pharma Cosmetix Research, LLC (US) 2022-07-27 — — EP claimed
EP-3157534-B1 ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS ATTILLAPS HOLDINGS (US) 2022-07-06 — — EP claimed
US-20220202739-A1 ENDOCANNABINOID MIMETIC AND ANTI-INFLAMMATORY COMPOUND CONTAINING COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF PHARMA COSMETIX RES LLC (US) 2022-06-30 — — US claimed
US-20220107305-A1 Companion Diagnostics for NSAIDS and Donepezil for Treating Specific Subpopulations of Patients Suffering from Alzheimer's Disease UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH 2022-04-07 — — US claimed
US-20220096420-A1 Acetylcholinesterase Inhibitors for Treatment of Dermatological Conditions ATTILLAPS HOLDINGS 2022-03-31 — — US claimed
EP-3965732-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING PRESBYOPIA AND METHODS FOR FABRICATING THEREOF Harrow IP, LLC (US) 2022-03-16 — — EP claimed
US-20220023368-A1 COMPOSITION COMPRISING CHICORY ROOT AND PEA CELL WALL FIBER FOR TREATING BRACHYSPIRA INFECTIONS COSUCRA GROUPE WARCOING S.A. (BE) 2022-01-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446241-B2 Treatment of ophthalmological conditions with acetylcholinesterase inhibitors ACHE, BCHE, PON1 ALDH1A1 427/4885NPC1 4067/4885MAPT 2492/4885
US-20220096420-A1 Acetylcholinesterase Inhibitors for Treatment of Dermatological Conditions ACHE, PON1, CYP17A1 ALDH1A1 370/4885NPC1 2143/4885MAPT 2062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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