Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350065 | 0.81 | HDAC6 (0.56) | ALDH1A1KMT2ASMN1; SMN2CCR8TPSAB1 | |
| SCHEMBL10327746 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2ASMN1; SMN2CCR8TPSAB1 | |
| SCHEMBL10194565 | 0.79 | SFRP1 (0.60) | ALDH1A1KMT2ASMN1; SMN2TPSAB1DPP4 | |
| SCHEMBL8350676 | 0.77 | KMT2A (0.44) | ALDH1A1KMT2ASMN1; SMN2CCR8TPSAB1 | |
| SCHEMBL10194631 | 0.76 | HDAC6 (0.57) | ALDH1A1KMT2ASMN1; SMN2TPSAB1DPP4 | |
| SCHEMBL13225618 | 0.72 | HDAC6 (0.48) | ALDH1A1KMT2ASMN1; SMN2TPSAB1SFRP1 | |
| SCHEMBL10194566 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KMT2ASMN1; SMN2CCR8TPSAB1 | |
| SCHEMBL14217565 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1KMT2ASMN1; SMN2CCR8TPSAB1 | |
| SCHEMBL10194626 | 0.70 | HDAC8 (0.50) | ALDH1A1KMT2ASMN1; SMN2CCR8DPP4 | |
| SCHEMBL2097769 | 0.68 | KMT2A (0.65) | ALDH1A1KMT2ASMN1; SMN2CCR8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485354-B1 | SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-05-28 | — | — | EP | disclosed |