Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725912 | 0.84 | GABRA1 (0.53) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL7311280 | 0.83 | CHRM1 (0.51) | — | |
| SCHEMBL7312587 | 0.81 | TP53 (0.39) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL11833620 | 0.79 | GABRA5 (0.44) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL11830651 | 0.78 | GABRA3 (0.42) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL7721718 | 0.78 | GABRA3 (0.38) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL11826182 | 0.76 | GABRA1 (0.47) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL11826517 | 0.76 | CHRM1 (0.47) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL8933495 | 0.76 | GABRA3 (0.41) | GABRA1GABRA5GABRA2GABRA3GABRB2 | |
| SCHEMBL8274468 | 0.76 | GABRA3 (0.51) | GABRA1GABRA5GABRA2GABRA3GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835424-B2 | Selective agents for pain suppression | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |
| EP-1925614-A1 | Anxiolytic agents with reduced sedative and ataxic effects | Wisys Technology Foundation, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |