Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | PTAFR | P25105 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933416 | 0.82 | GABRA3 (0.35) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11833620 | 0.80 | GABRA5 (0.44) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL14217666 | 0.76 | GABRA1 (0.55) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL7415888 | 0.74 | GABRA3 (0.47) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11827503 | 0.73 | GABRA1 (0.45) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11830651 | 0.71 | GABRA3 (0.42) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11158188 | 0.71 | TP53 (0.39) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11827831 | 0.70 | GABRA1 (0.48) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11826182 | 0.69 | GABRA1 (0.47) | GABRA3GABRA5GABRA1GABRA2GABRB2 | |
| SCHEMBL11826517 | 0.69 | CHRM1 (0.47) | GABRA3GABRA5GABRA1GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |