Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 12/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882540 | 1.00 | ITGB3 (0.60) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL14420637 | 0.90 | CCR5 (0.54) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL4130344 | 0.90 | CCR5 (0.54) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL14416420 | 0.89 | CCR5 (0.53) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL22904305 | 0.88 | KCNQ3 (0.65) | CCR5KCNQ3KCNQ2KCNH2CYP3A4 | |
| SCHEMBL22904186 | 0.88 | KCNQ3 (0.65) | CCR5KCNQ3KCNQ2KCNH2CYP3A4 | |
| SCHEMBL16201140 | 0.88 | CCR5 (0.52) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL9829153 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BSMN1; SMN2CCR5KCNQ3 | |
| SCHEMBL27617486 | 0.87 | CCR5 (0.53) | ITGB3ITGA2BCCR5KCNQ3KCNQ2 | |
| SCHEMBL3881134 | 0.86 | CCR5 (0.57) | ITGB3ITGA2BCCR5KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556899-B2 | Method for preparing Maraviroc | SCI PHARMTECH, INC. (TW) | 2020-02-11 | — | — | US | disclosed |
| US-20190248782-A1 | METHOD FOR PREPARING MARAVIROC | SCI PHARMTECH, INC. (TW) | 2019-08-15 | — | — | US | disclosed |
| US-7368460-B2 | Tropane derivatives useful in therapy | PFIZER, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070218486-A1 | Immunoassays, Haptens, Immunogens and Antibodies for Anti-HIV Therapeutics | ARK DIAGNOSTICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070218486-A1 | Immunoassays, Haptens, Immunogens and Antibodies for Anti-HIV Therapeutics | ARK DIAGNOSTICS, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007103740-A2 | IMMUNOASSAYS, HAPTENS, IMMUNOGENS AND ANTIBODIES FOR ANTI-HIV THERAPEUTICS | ARK DIAGNOSTICS (US) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556899-B2 | Method for preparing Maraviroc | CYP3A43, NAT10, CYP3A5 | ITGB3 1945/4885ITGA2B 3699/4885SMN1; SMN2 4253/4885 |
| US-20190248782-A1 | METHOD FOR PREPARING MARAVIROC | CYP3A43, NAT10, CYP3A5 | ITGB3 1945/4885ITGA2B 3699/4885SMN1; SMN2 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.