Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 1/20 | 0.52 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696193 | 0.94 | SMN1; SMN2 (0.67) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL9830370 | 0.94 | SMN1; SMN2 (0.63) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL4696189 | 0.94 | SMN1; SMN2 (0.67) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL4138087 | 0.94 | SMN1; SMN2 (0.63) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| Formic Acid SCHEMBL27557118 | 0.89 | SMN1; SMN2 (0.58) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL14218307 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL3882540 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2BSMN1; SMN2LMNARECQL | |
| SCHEMBL4130312 | 0.82 | RECQL (0.62) | SMN1; SMN2LMNARECQLCCR5KMT2A | |
| SCHEMBL5424938 | 0.82 | LMNA (0.61) | SMN1; SMN2LMNARECQLCCR5KMT2A | |
| Hydrochloric Acid SCHEMBL7290839 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2BSMN1; SMN2LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |