Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986584 | 0.88 | ALDH1A1 (0.46) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL219096 | 0.88 | TUBB4A (0.55) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28275397 | 0.88 | TUBB4A (0.55) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3355977 | 0.83 | TPMT (0.68) | TPMTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL17946064 | 0.83 | MEN1 (0.47) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL786462 | 0.83 | LMNA (0.60) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24425750 | 0.81 | KMT2A (0.54) | TPMTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL27189692 | 0.81 | ALDH1A1 (0.68) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30822595 | 0.81 | ALDH1A1 (0.68) | TPMTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL668639 | 0.80 | RXFP1 (0.56) | TPMTKMT2AALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060578-A2 | 3-ARYL-6-ARYL-[1,2,4] TRIAZOLO[3,4-B][1,3,4] THIADIAZOLES AND RELATED COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2008-05-22 | — | — | WO | disclosed |