Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696642 | 0.87 | KMT2A (0.59) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL13298324 | 0.85 | TDP1 (0.48) | SMN1; SMN2MAPTTDP1LMNAALDH1A1 | |
| SCHEMBL1205813 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL9765294 | 0.81 | MAPT (0.54) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL120180 | 0.81 | KMT2A (0.59) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL13290651 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL18087017 | 0.81 | LMNA (0.53) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL10625899 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL13290630 | 0.80 | MAPT (0.53) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA | |
| SCHEMBL11704915 | 0.80 | MAPT (0.53) | SMN1; SMN2MAPTL3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368563-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | APOB, NPC1L1, CYP46A1 | SMN1; SMN2 207/4885MAPT 3636/4885L3MBTL1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.