Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18087017 | 0.94 | LMNA (0.53) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL28905911 | 0.90 | LMNA (0.50) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL248163 | 0.89 | GAA (0.50) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL14218905 | 0.87 | SMN1; SMN2 (0.54) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL6610147 | 0.86 | KMT2A (0.46) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL19294787 | 0.85 | KMT2A (0.46) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL10311842 | 0.84 | BCL9 (0.67) | KMT2ALMNAALDH1A1MAPTHSD17B10 | |
| SCHEMBL28627409 | 0.84 | LMNA (0.52) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL10824946 | 0.82 | ALDH1A1 (0.56) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL13298324 | 0.82 | TDP1 (0.48) | KMT2ALMNAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112050-A1 | HMGCoA reductase inhibitor combinations and uses thereof | PSIVIDA INC. (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070112050-A1 | HMGCoA reductase inhibitor combinations and uses thereof | PSIVIDA INC. (US) | 2007-05-17 | — | — | US | disclosed |
| EP-1118644-B1 | Hot melt printing ink | SIEGWERK DRUCKFARBEN AG (DE) | 2006-06-14 | — | — | EP | disclosed |
| EP-1118644-A2 | Hot melt printing ink | Siegwerk Druckfarben GmbH & Co. KG (DE) | 2001-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112050-A1 | HMGCoA reductase inhibitor combinations and uses thereof | HMGCR, HMGB2, HMGB3 | KMT2A 973/4885LMNA 394/4885ALDH1A1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.