Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.63 |
| ▸ | THRA | P10827 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219064 | 0.88 | THRB (0.53) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14219181 | 0.88 | ALDH5A1 (0.51) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14192435 | 0.84 | THRB (0.90) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL14219182 | 0.83 | GAA (0.42) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14192427 | 0.82 | THRB (0.70) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL14192478 | 0.81 | THRB (0.68) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14192518 | 0.81 | THRB (0.68) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL14192452 | 0.81 | THRB (0.68) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL14192423 | 0.81 | THRB (0.68) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL14192472 | 0.80 | THRB (0.67) | THRBTHRAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |