Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.53 |
| ▸ | THRA | P10827 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219181 | 0.91 | ALDH5A1 (0.51) | THRBTHRAKMT2AMEN1ALDH5A1 | |
| SCHEMBL14219183 | 0.88 | THRB (0.63) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14219182 | 0.86 | GAA (0.42) | THRBTHRAKMT2AMEN1KDM4E | |
| SCHEMBL14218976 | 0.84 | THRB (0.42) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14218996 | 0.82 | CYP2C9 (0.52) | THRBTHRAKMT2AMEN1TAS1R3 | |
| SCHEMBL14219065 | 0.81 | THRB (0.40) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL1952125 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1TP53MAPK1 | |
| SCHEMBL14219059 | 0.80 | CYP2C9 (0.49) | THRBTHRAKMT2AMEN1TAS1R3 | |
| SCHEMBL2398606 | 0.79 | KMT2A (0.50) | THRBKMT2ATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL11966992 | 0.79 | THRB (0.41) | THRBKMT2ATAS1R3TAS1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |