Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219064 | 0.86 | THRB (0.53) | SMN1; SMN2KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL14219181 | 0.85 | ALDH5A1 (0.51) | SMN1; SMN2ALDH1A1MAPTTHRBRAB9A | |
| SCHEMBL14219183 | 0.83 | THRB (0.63) | ALDH1A1MAPTTHRBRAB9ATHRA | |
| SCHEMBL14118267 | 0.79 | ALDH5A1 (0.52) | ALDH1A1MAPTMMP2MMP3THRB | |
| SCHEMBL8603370 | 0.77 | MGLL (0.42) | KDM4EALDH1A1MMP2MMP3THRB | |
| SCHEMBL8603390 | 0.77 | MMP2 (0.43) | KDM4EALDH1A1MAPTMMP2MMP3 | |
| SCHEMBL14219065 | 0.76 | THRB (0.40) | SMN1; SMN2ALDH1A1MAPTTHRBTHRA | |
| SCHEMBL13283120 | 0.75 | ACACB (0.44) | THRB | |
| SCHEMBL5105673 | 0.75 | ALDH5A1 (0.57) | SMN1; SMN2KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL4273346 | 0.74 | PPARG (0.55) | KDM4EALDH1A1MMP2MMP3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |