Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | PTEN | P60484 | 1/20 | 0.31 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078852 | 0.85 | KEAP1 (0.47) | PTPRBCDC25ACDC25BPTENPTPMT1 | |
| SCHEMBL4074845 | 0.81 | CYP4F2 (0.41) | GAAMAPTALDH1A1OPRM1OPRD1 | |
| SCHEMBL4070940 | 0.79 | CYP4F2 (0.41) | — | |
| SCHEMBL13933508 | 0.78 | ALDH1A1 (0.56) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL4074913 | 0.78 | ALDH1A1 (0.56) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL4073293 | 0.76 | AKR1B1 (0.44) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1107169 | 0.71 | TAAR1 (0.55) | ALDH1A1FFAR1MEN1KMT2AFFAR4 | |
| SCHEMBL13176544 | 0.69 | DRD2 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19803699 | 0.67 | TAAR1 (0.55) | ALDH1A1FFAR1MEN1KMT2AFFAR4 | |
| SCHEMBL13082819 | 0.67 | KEAP1 (0.58) | MAPTALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908472-A1 | Silicon derivatives for PET imaging | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-09 | — | — | EP | disclosed |