Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220016 | 0.85 | CYP2C9 (0.39) | APPNPC1RAB9AESR2FFAR1 | |
| SCHEMBL14219382 | 0.85 | ACACB (0.34) | APPNPC1RAB9AFFAR1OPRM1 | |
| SCHEMBL14219568 | 0.83 | NPC1 (0.42) | NPC1RAB9AESR2FFAR1SOS1 | |
| SCHEMBL14219462 | 0.82 | CCR1 (0.39) | OPRM1CCR5CCR1 | |
| SCHEMBL14219385 | 0.81 | DGAT1 (0.33) | APPNPC1RAB9AFFAR1DGAT1 | |
| SCHEMBL14219310 | 0.81 | DGAT1 (0.33) | APPNPC1RAB9AFFAR1DGAT1 | |
| SCHEMBL14220025 | 0.80 | ADRB2 (0.39) | CCR1PRCP | |
| SCHEMBL14219465 | 0.80 | ADRB2 (0.39) | CCR1PRCP | |
| SCHEMBL14219905 | 0.77 | OPRM1 (0.39) | NPC1RAB9AOPRM1 | |
| SCHEMBL14219377 | 0.77 | OPRM1 (0.39) | NPC1RAB9AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |