SCHEMBL14219830

SCHEMBL14219830

COc1cc(C(CC(C)(C)C)C(C)(C)C)ccc1OC(C)OCCC1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.37
HIF1A Q16665 2/20 0.36
NR3C1 P04150 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
PDGFRB P09619 1/20 0.34
PDGFRA P16234 1/20 0.34
EPHA2 P29317 1/20 0.33
KDR P35968 1/20 0.33
EPHB4 P54760 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14220826 0.90 HPGD (0.39) HPGDALDH1A1TSHR
SCHEMBL11960786 0.88 HPGD (0.36) HPGDNR3C1
SCHEMBL13359730 0.86 HPGD (0.42) HPGDHIF1ANR3C1NPSR1PDGFRB
SCHEMBL10088186 0.84 NR3C1 (0.38) HPGDHIF1ANR3C1NPSR1PDGFRB
SCHEMBL11960820 0.83 NFE2L2 (0.38) HPGDALDH1A1
SCHEMBL11960784 0.83 NFE2L2 (0.38) HPGDALDH1A1
SCHEMBL14220824 0.80 HPGD (0.38) HPGDHIF1ANR3C1NPSR1PDGFRB
SCHEMBL22762299 0.78 NPSR1 (0.36) HPGDHIF1ANR3C1NPSR1PDGFRB
SCHEMBL11960893 0.77 HRH3 (0.37) HPGDPDGFRBALDH1A1RAB9A
SCHEMBL11960798 0.77 HRH3 (0.37) HPGDPDGFRBALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314938-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-05 US disclosed
EP-1906248-A1 Resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314938-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN HCAR1, H1-0, H1-10 HPGD 1467/4885HIF1A 285/4885NR3C1 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.