Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220125 | 0.89 | MAP2K1 (0.38) | MAP2K2MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL14219717 | 0.89 | PTGS2 (0.38) | MAP2K2MAP2K1PTGS2EGFRMEN1 | |
| SCHEMBL14219845 | 0.85 | MAP2K2 (0.35) | MAP2K2MAP2K1PTGS2 | |
| SCHEMBL14220115 | 0.79 | TDP1 (0.38) | MAP2K2MAP2K1PTGS2EGFRMEN1 | |
| SCHEMBL14219723 | 0.79 | MAP2K1 (0.39) | MAP2K2MAP2K1EGFRMEN1KMT2A | |
| SCHEMBL14219642 | 0.77 | TDP1 (0.39) | MAP2K1PTGS2EGFRMEN1KMT2A | |
| SCHEMBL14222505 | 0.76 | MEN1 (0.41) | MAP2K2MAP2K1MEN1KMT2ATDP1 | |
| SCHEMBL14223203 | 0.75 | KDM4E (0.36) | MAP2K2MAP2K1PTGS2EGFRMEN1 | |
| SCHEMBL14219656 | 0.75 | PTGS2 (0.41) | MAP2K2MAP2K1PTGS2EGFRMEN1 | |
| SCHEMBL14219715 | 0.75 | PTGS2 (0.41) | MAP2K1PTGS2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |