Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219856 | 0.85 | MAP2K1 (0.39) | MAP2K2MAP2K1DHODH | |
| SCHEMBL14220124 | 0.85 | MAP2K2 (0.36) | MAP2K2MAP2K1PTGS2 | |
| SCHEMBL14223203 | 0.81 | KDM4E (0.36) | MAP2K2MAP2K1DHODHPTGS2 | |
| SCHEMBL14220128 | 0.80 | PTGS2 (0.37) | MAP2K2MAP2K1DHODHPTGS2 | |
| SCHEMBL14219853 | 0.78 | MAP2K1 (0.40) | MAP2K2MAP2K1DHODH | |
| SCHEMBL14219642 | 0.77 | TDP1 (0.39) | MAP2K1DHODHPTGS2 | |
| SCHEMBL14220111 | 0.76 | ALDH1A1 (0.40) | MAP2K1DHODH | |
| SCHEMBL14219646 | 0.76 | MEN1 (0.39) | MAP2K2MAP2K1DHODH | |
| SCHEMBL14219614 | 0.76 | MAP2K1 (0.42) | MAP2K2MAP2K1 | |
| SCHEMBL14219656 | 0.75 | PTGS2 (0.41) | MAP2K2MAP2K1DHODHPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |