Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMC2 | O95347 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.30 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220128 | 0.90 | PTGS2 (0.37) | PTGS2CNR1CNR2DHODHNPC1 | |
| SCHEMBL14219642 | 0.89 | TDP1 (0.39) | PTGS2LCKDHODHNPC1RAB9A | |
| SCHEMBL14219717 | 0.87 | PTGS2 (0.38) | PTGS2CNR1CNR2SCN9AEGFR | |
| SCHEMBL14219715 | 0.83 | PTGS2 (0.41) | PTGS2CNR1CNR2DHODHRAB9A | |
| SCHEMBL14220130 | 0.83 | ALDH1A1 (0.37) | LCKDHODHNPC1RAB9AEGFR | |
| SCHEMBL14219683 | 0.82 | LMNA (0.42) | LCKDHODHNPC1RAB9AMAP2K1 | |
| SCHEMBL14220117 | 0.81 | MEN1 (0.51) | SCN9AEGFRMAP2K1SMC2CSNK2A2 | |
| SCHEMBL14220114 | 0.81 | PTGS2 (0.34) | PTGS2DHODHEGFRMAP2K1IRAK4 | |
| SCHEMBL14223052 | 0.81 | MAP2K1 (0.45) | EGFRMAP2K1SMC2CSNK2A2MAP2K2 | |
| SCHEMBL14219843 | 0.81 | MAP2K1 (0.45) | EGFRMAP2K1SMC2CSNK2A2MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |