Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14196129 | 0.93 | DRD4 (0.51) | DRD4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12064278 | 0.88 | DRD4 (0.51) | DRD4ALDH1A1MEN1KMT2A | |
| SCHEMBL10287218 | 0.86 | ALDH1A1 (0.56) | SMN1; SMN2LMNAALDH1A1HTTMEN1 | |
| SCHEMBL1109163 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2LMNAALDH1A1HTTTDP1 | |
| SCHEMBL1109453 | 0.84 | NPC1 (0.54) | SMN1; SMN2LMNAALDH1A1HTTTDP1 | |
| SCHEMBL1109291 | 0.84 | L3MBTL1 (0.58) | SMN1; SMN2LMNAALDH1A1HTTTDP1 | |
| SCHEMBL1109357 | 0.83 | NPC1 (0.53) | SMN1; SMN2ALDH1A1HTTTDP1MEN1 | |
| SCHEMBL1109198 | 0.83 | NPC1 (0.53) | SMN1; SMN2ALDH1A1HTTTDP1MEN1 | |
| SCHEMBL1109284 | 0.82 | LMNA (0.47) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10287204 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |