Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224372 | 0.93 | DRD4 (0.54) | DRD4LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL404928 | 0.89 | DRD2 (0.48) | DRD4 | |
| SCHEMBL405409 | 0.86 | TSHR (0.54) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL403957 | 0.85 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL404637 | 0.85 | NPC1 (0.51) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL404913 | 0.84 | L3MBTL1 (0.55) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL403977 | 0.84 | NPC1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL439727 | 0.84 | NPC1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL399640 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL438343 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |