Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224801 | 0.93 | CYP11B2 (0.39) | HDAC1HDAC2HDAC8SMN1; SMN2HPSE | |
| SCHEMBL14224552 | 0.91 | SMN1; SMN2 (0.43) | GAASMN1; SMN2NPSR1L3MBTL1NR2E3 | |
| SCHEMBL14224553 | 0.88 | AURKA (0.35) | HDAC1HDAC2HDAC8GAASMN1; SMN2 | |
| SCHEMBL14224555 | 0.87 | AURKA (0.34) | HDAC1HDAC2HDAC8GAASMN1; SMN2 | |
| SCHEMBL14224802 | 0.84 | MAPT (0.41) | GAASMN1; SMN2NPSR1L3MBTL1MLLT1 | |
| SCHEMBL14224525 | 0.84 | MAPT (0.35) | HDAC1HDAC2HDAC8HPSEMAPT | |
| SCHEMBL14224529 | 0.82 | FOXO1 (0.41) | SMN1; SMN2HPSEALDH1A1PKMMAPT | |
| SCHEMBL14224798 | 0.82 | CYP11B2 (0.40) | HDAC1HDAC2HDAC8MLLT1CDK1 | |
| SCHEMBL14224793 | 0.81 | CYP11B2 (0.36) | HDAC1HDAC2HDAC8MLLT1CDK1 | |
| SCHEMBL14224756 | 0.80 | MAPT (0.42) | SMN1; SMN2NPSR1ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | QTRT1, Q6ZSR9, QTRT2 | HDAC1 339/4885HDAC2 383/4885HDAC8 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.