Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224802 | 0.93 | MAPT (0.41) | SMN1; SMN2GAANPSR1L3MBTL1MAPT | |
| SCHEMBL14224529 | 0.92 | FOXO1 (0.41) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL14224550 | 0.91 | HDAC1 (0.34) | SMN1; SMN2GAANPSR1L3MBTL1MAPT | |
| SCHEMBL14224553 | 0.90 | AURKA (0.35) | SMN1; SMN2GAANPSR1L3MBTL1FSCN1 | |
| SCHEMBL14224555 | 0.86 | AURKA (0.34) | SMN1; SMN2GAANPSR1L3MBTL1KDM4E | |
| SCHEMBL14224801 | 0.85 | CYP11B2 (0.39) | SMN1; SMN2MAPTTP53KDM4EMEN1 | |
| SCHEMBL14224675 | 0.85 | MAPT (0.43) | SMN1; SMN2GAANPSR1L3MBTL1MAPT | |
| SCHEMBL14224539 | 0.84 | NPC1 (0.43) | SMN1; SMN2NPSR1MAPTTP53KDM4E | |
| SCHEMBL14224524 | 0.84 | MAPT (0.37) | SMN1; SMN2MAPTTP53KDM4ELMNA | |
| SCHEMBL14224798 | 0.83 | CYP11B2 (0.40) | HTTNPC1RAB9APRKCAFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | QTRT1, Q6ZSR9, QTRT2 | SMN1; SMN2 4635/4885GAA 1169/4885NPSR1 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.