Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.51 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197239 | 0.87 | ACHE (0.46) | ACHEFGFR1FGFR2FGFR3RUNX1 | |
| SCHEMBL14224667 | 0.81 | ACHE (0.67) | ACHEFGFR1FGFR2FGFR3RUNX1 | |
| SCHEMBL14224496 | 0.79 | TERT (0.64) | RAB9AHPGDATMKDM4E | |
| SCHEMBL28521762 | 0.72 | ALDH1A1 (0.61) | ACHEFGFR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3380635 | 0.72 | ACHE (0.55) | ACHEFGFR1FGFR2FGFR3RUNX1 | |
| SCHEMBL10280168 | 0.72 | FGFR1 (0.58) | FGFR1FGFR2FGFR3ALDH1A1HPGD | |
| SCHEMBL27819847 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPT | |
| SCHEMBL14189696 | 0.69 | ACHE (0.57) | ACHENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL12109508 | 0.69 | CBFB (0.57) | FGFR1FGFR2FGFR3NPC1RAB9A | |
| SCHEMBL28426065 | 0.68 | HRH4 (0.62) | ACHEFGFR1FGFR2FGFR3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-04-17 | — | — | US | disclosed |
| US-7265129-B2 | Anti-infective biaryl compounds | GENESOFT PHARMACEUTICALS, INC. (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | QTRT1, Q6ZSR9, QTRT2 | ACHE 634/4885FGFR1 4274/4885FGFR2 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.