Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458268 | 0.84 | CA2 (0.61) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL805430 | 0.82 | NR5A2 (0.48) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL12240426 | 0.82 | CA2 (0.59) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL2811722 | 0.82 | CA2 (0.65) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL12651295 | 0.82 | SMN1; SMN2 (0.63) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL13299510 | 0.81 | CA2 (0.42) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL13178842 | 0.81 | CA2 (0.42) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL12189382 | 0.80 | BACE1 (0.37) | ALDH1A1ALOX15LMNAGABRA1GABRB2 | |
| SCHEMBL6434030 | 0.79 | HSPA5 (0.46) | CA2CA1ALDH1A1SMN1; SMN2TYR | |
| SCHEMBL11985297 | 0.78 | CA2 (0.65) | CA2CA1ALDH1A1SMN1; SMN2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399073-B2 | Liquid-crystal medium | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-20130056680-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| US-8349415-B2 | Liquid-crystalline medium and liquid-crystal display having high twist | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120326085-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120273723-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-01 | — | — | US | disclosed |
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20120248374-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080197319-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080193681-A1 | Liquid-Crystal Medium | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| US-7390538-B2 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2008-06-24 | — | — | US | disclosed |
| US-7351453-B2 | Mixture of polar compounds of biphenyls, cyclohexane and phenyl substituted biphenyl; fast response time, a low threshold voltage, low temperature stability | MERCK PATENT GMBH (DE) | 2008-04-01 | — | — | US | disclosed |
| US-20070080324-A1 | mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-7189440-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034830-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications. | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120326084-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, PLG | CA2 4194/4885CA1 1832/4885ALDH1A1 948/4885 |
| US-20120273723-A1 | LIQUID CRYSTAL MEDIUM | CHRM1, L1CAM, ZYX | CA2 423/4885CA1 134/4885ALDH1A1 1107/4885 |
| US-20120248374-A1 | LIQUID CRYSTALLINE MEDIUM | LBR, CTNND1, VIM | CA2 1159/4885CA1 935/4885ALDH1A1 3596/4885 |
| US-20120268706-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, FLNB | CA2 1948/4885CA1 998/4885ALDH1A1 3557/4885 |
| US-20120326085-A1 | LIQUID-CRYSTALLINE MEDIUM | TLL1, LAS1L, LOXL1 | CA2 359/4885CA1 138/4885ALDH1A1 1990/4885 |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | CUTA, NEFM, FES | CA2 4005/4885CA1 2201/4885ALDH1A1 2243/4885 |
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | L1CAM, NEFM, CHRM1 | CA2 1322/4885CA1 270/4885ALDH1A1 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.