Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224783 | 0.86 | RPS6KA5 (0.48) | AURKANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL14224797 | 0.81 | NPC1 (0.63) | NPC1ALDH1A1PKMKDM4ERAB9A | |
| SCHEMBL1170780 | 0.76 | ALDH1A1 (0.68) | AURKANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL14224791 | 0.75 | KDM4E (0.40) | AURKANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL14224799 | 0.74 | KDM4E (0.38) | NPC1ALDH1A1PKMKDM4ERAB9A | |
| SCHEMBL16331618 | 0.74 | ALDH1A1 (0.71) | AURKANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL26426627 | 0.73 | PDE5A (0.51) | AURKANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL23745062 | 0.73 | RAB9A (0.51) | RAB9A | |
| SCHEMBL14224800 | 0.71 | KDM4E (0.30) | NPC1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL26426622 | 0.71 | PDE5A (0.52) | AURKANPC1ALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | QTRT1, Q6ZSR9, QTRT2 | AURKA 857/4885NPC1 796/4885ALDH1A1 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.