Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13919671 | 0.75 | HDAC1 (0.48) | F10MAPTKDM4EHPGDPOLB | |
| SCHEMBL14224752 | 0.74 | PRSS12 (0.42) | CASP3SENP8SENP7SENP6F10 | |
| SCHEMBL14224803 | 0.72 | FPR1 (0.42) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL14427753 | 0.71 | SMN1; SMN2 (0.41) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL14224805 | 0.70 | HDAC1 (0.33) | CASP3SENP8SENP7SENP6PRSS12 | |
| SCHEMBL13919908 | 0.70 | F10 (0.43) | F10TLR8PRSS12ALDH1A1KMT2A | |
| SCHEMBL14427754 | 0.69 | L3MBTL1 (0.42) | ALDH1A1MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL13919912 | 0.67 | F10 (0.45) | CASP3SENP8SENP7SENP6F10 | |
| SCHEMBL13919939 | 0.67 | HRAS (0.42) | ALDH1A1KMT2AMAPTKDM4ECYP3A4 | |
| SCHEMBL14224538 | 0.65 | AVPR2 (0.45) | ALDH1A1KMT2AMAPTMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-04-17 | — | — | US | disclosed |
| US-7265129-B2 | Anti-infective biaryl compounds | GENESOFT PHARMACEUTICALS, INC. (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090816-A1 | ANTI-INFECTIVE BIARYL COMPOUNDS | QTRT1, Q6ZSR9, QTRT2 | CASP3 22/4885SENP8 3347/4885SENP7 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.