Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436933 | 0.83 | — | — | |
| SCHEMBL1908164 | 0.79 | — | — | |
| SCHEMBL16435884 | 0.77 | GAA (0.38) | — | |
| SCHEMBL16435879 | 0.77 | HSD11B1 (0.35) | — | |
| SCHEMBL13749381 | 0.77 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL16435892 | 0.77 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL17108226 | 0.75 | KDM4E (0.30) | KDM4ELMNACYP2C19 | |
| SCHEMBL140244 | 0.72 | — | — | |
| SCHEMBL16435877 | 0.72 | KDM4E (0.32) | KDM4ELMNACYP2C19 | |
| SCHEMBL13951785 | 0.72 | KDM4E (0.32) | KDM4ELMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096830-A1 | Anti-Inflammatory Macrolide Conjugates | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096830-A1 | Anti-Inflammatory Macrolide Conjugates | NLRP3, IL1B, MPO | KDM4E 1742/4885LMNA 1141/4885CYP2C19 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.