Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227329 | 0.90 | MEN1 (0.82) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL14227330 | 0.89 | KMT2A (0.67) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL14227314 | 0.87 | MEN1 (0.70) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL9973845 | 0.87 | TOP1 (0.59) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL4669087 | 0.84 | MEN1 (0.65) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL6095280 | 0.83 | CHEK1 (0.63) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL9973843 | 0.82 | TOP1 (0.58) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL6092606 | 0.80 | CHEK1 (0.63) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL6092491 | 0.80 | AKR1C4 (0.68) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL637477 | 0.79 | KMT2A (0.70) | MEN1KMT2AMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129036-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | SYMRISE AG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-8409552-B2 | Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds | SYMRISE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | SYMRISE AG (DE) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129036-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | HPD, CYP4A22, PAH | MEN1 2409/4885KMT2A 2584/4885MAPT 1788/4885 |
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | CMA1, TPSAB1, HRH1 | MEN1 1612/4885KMT2A 1414/4885MAPT 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.