Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041469 | 0.80 | PTPN1 (0.63) | PTPN1MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL14228206 | 0.79 | SENP5 (0.49) | — | |
| SCHEMBL1396290 | 0.78 | ALDH1A1 (0.57) | PTPN1MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL14228419 | 0.78 | GLRA1 (0.48) | PTPN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL23190746 | 0.77 | MCL1 (0.48) | PTPN1MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL12253970 | 0.77 | PTPN1 (0.47) | PTPN1MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL3424839 | 0.77 | ALDH1A1 (0.55) | MCL1PTGER1L3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL18037169 | 0.77 | ALDH1A1 (0.55) | PTPN1MCL1PTGER1PTGER4PTGER3 | |
| SCHEMBL14228207 | 0.76 | MEN1 (0.46) | ALDH1A1MAPTSMN1; SMN2MAOB | |
| SCHEMBL15726040 | 0.76 | PTGER1 (0.57) | PTPN1MCL1PTGER1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | PTPN1 806/4885MCL1 4113/4885PTGER1 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.