Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229498 | 0.91 | GAA (0.34) | GAAS1PR1 | |
| SCHEMBL14229322 | 0.88 | MLYCD (0.33) | POLBGAAMAPTCA1MLYCD | |
| SCHEMBL14230195 | 0.88 | POLB (0.34) | POLBMLYCDS1PR1 | |
| SCHEMBL14230059 | 0.87 | SMN1; SMN2 (0.33) | POLBGAAMAPTS1PR1 | |
| SCHEMBL14201121 | 0.86 | MLYCD (0.32) | POLBMLYCDS1PR1 | |
| SCHEMBL14229087 | 0.85 | GAA (0.34) | GAAS1PR1 | |
| SCHEMBL14230196 | 0.85 | CYP1A2 (0.34) | S1PR1 | |
| SCHEMBL14229889 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL14230193 | 0.84 | MLYCD (0.31) | POLBMLYCDS1PR1 | |
| SCHEMBL14201151 | 0.81 | POLB (0.32) | POLBMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |