Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721524 | 0.88 | ALDH1A1 (0.68) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 | |
| SCHEMBL3464451 | 0.84 | FDPS (0.54) | ALDH1A1HPGDTRIM24ALDH5A1ABAT | |
| Isovanillin SCHEMBL28418805 | 0.81 | ALDH1A1 (0.73) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 | |
| SCHEMBL27804316 | 0.80 | FDPS (0.42) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 | |
| SCHEMBL944430 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDRAB9ATTRTSHR | |
| SCHEMBL31247739 | 0.80 | FDPS (0.42) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 | |
| SCHEMBL4617044 | 0.80 | TSHR (0.44) | ALDH1A1HPGDKDM4ERAB9ATSHR | |
| SCHEMBL18095839 | 0.80 | ALDH1A1 (0.49) | ALDH1A1AOX1HPGDKDM4ETSHR | |
| SCHEMBL15853568 | 0.79 | ALDH1A1 (0.61) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 | |
| SCHEMBL16472557 | 0.79 | ALDH1A1 (0.61) | ALDH1A1AOX1HPGDTRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117653618-A | Novel benzalacetone derivative and use thereof | 韩药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110996930-B | Novel benzalacetone derivative and use thereof | 韩药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11629121-B2 | Benzylideneacetone derivative and use thereof | KORPHARM CO., LTD. (KR) | 2023-04-18 | — | — | US | disclosed |
| US-20210139414-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | KORPHARM CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
| US-20210139414-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | KORPHARM CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
| EP-3659592-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | Korpharm Co., Ltd. (KR) | 2020-06-03 | — | — | EP | disclosed |
| CN-110996930-A | Novel benzylidene acetone derivative and use thereof | 韩药有限公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-2225205-B1 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2013-01-02 | — | — | EP | disclosed |
| US-7968724-B2 | Ester derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-06-28 | — | — | US | disclosed |
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| EP-2296476-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | Microbiotix, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |
| EP-2225205-A1 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009077068-A9 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2009-08-20 | — | — | WO | disclosed |
| US-20090170903-A1 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2009-07-02 | — | — | US | disclosed |
| WO-2009077068-A1 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070913-A1 | Ester derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.p.A. (IT) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | BLVRB, TFPI, FOSB | ALDH1A1 1408/4885AOX1 268/4885HPGD 378/4885 |
| US-20210139414-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | EBP, CREBBP, BPTF | ALDH1A1 34/4885AOX1 417/4885HPGD 192/4885 |
| US-20090170903-A1 | ESTER DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE5A | ALDH1A1 579/4885AOX1 1304/4885HPGD 429/4885 |
| US-11629121-B2 | Benzylideneacetone derivative and use thereof | GNPAT, NAT1, ALDH7A1 | ALDH1A1 6/4885AOX1 1096/4885HPGD 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.