Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229379 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14229025 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14229114 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14200443 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14229347 | 0.85 | TAS1R3 (0.45) | ALDH1A1MAPTNPC1TP53HPGD | |
| SCHEMBL14229350 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14229349 | 0.84 | TP53 (0.40) | MAPTTP53 | |
| SCHEMBL14229231 | 0.84 | L3MBTL1 (0.40) | ALDH1A1MAPTNPC1GAATP53 | |
| SCHEMBL14229144 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1GAANPSR1 | |
| SCHEMBL14230213 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTNPC1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |