Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 15/20 | 0.62 |
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14230042 | 0.86 | PCNA (0.64) | PCNAPOLBTHRATHRBMAPK1 | |
| SCHEMBL14230043 | 0.84 | THRB (0.56) | PCNAPOLBTHRATHRBMAPK1 | |
| SCHEMBL22382794 | 0.83 | PCNA (0.67) | PCNALIG1POLBTHRATHRB | |
| SCHEMBL14230065 | 0.83 | TAAR5 (0.68) | PCNALIG1 | |
| SCHEMBL14264010 | 0.80 | PCNA (0.67) | PCNALIG1POLBTHRATHRB | |
| SCHEMBL13886598 | 0.80 | TAAR5 (0.68) | PCNALIG1POLBTHRATHRB | |
| SCHEMBL14230075 | 0.79 | ESR1 (0.52) | — | |
| SCHEMBL16124480 | 0.78 | PCNA (0.63) | PCNALIG1 | |
| SCHEMBL4005004 | 0.78 | PCNA (0.66) | PCNALIG1POLBTHRATHRB | |
| SCHEMBL4004003 | 0.77 | PCNA (0.58) | PCNALIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-08 | — | — | US | disclosed |
| US-7339079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |