Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431292 | 0.82 | AR (0.49) | PTGDR2PGRAR | |
| SCHEMBL2428149 | 0.75 | AR (0.47) | PTGDR2PGRAR | |
| SCHEMBL14231949 | 0.71 | — | — | |
| SCHEMBL14231582 | 0.70 | PGR (0.46) | PTGDR2PGRARKDM4EGAA | |
| SCHEMBL2428087 | 0.69 | AR (0.43) | PGRAR | |
| SCHEMBL14232156 | 0.68 | RORA (0.34) | — | |
| SCHEMBL3104074 | 0.64 | NOTUM (0.44) | PTGDR2KDM4EPTGS2 | |
| SCHEMBL15486713 | 0.63 | DNMT1 (0.45) | PTGDR2MCL1 | |
| SCHEMBL948599 | 0.63 | ALDH1A1 (0.41) | PTGDR2KDM4EGAAALDH1A1 | |
| SCHEMBL11397353 | 0.62 | ALDH1A1 (0.41) | PTGDR2KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042571-A2 | SUBSTITUTED INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-10 | — | — | WO | disclosed |