Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016945 | 0.83 | CYP2C19 (0.52) | GLSHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL819824 | 0.80 | GLS (0.46) | GLSHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL819828 | 0.80 | KMT2A (0.58) | GLSHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL6802549 | 0.80 | EPHX1 (0.58) | GLSHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL13379421 | 0.79 | LMNA (0.54) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13379420 | 0.79 | LMNA (0.54) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2445922 | 0.79 | LMNA (0.54) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL23658188 | 0.78 | TAAR1 (0.50) | GLSCYP2C19EPHX1 | |
| SCHEMBL5196291 | 0.77 | GLS (0.53) | GLSHPGDTSHRALDH1A1KMT2A | |
| SCHEMBL819324 | 0.77 | MMP8 (0.51) | KDM4EKMT2ACHRM1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | disclosed |