SCHEMBL9634830

SCHEMBL9634830

Cc1ccccc1S(=O)(=O)c1cccc(C)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
HSD11B1 P28845 1/20 0.44
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
POLB P06746 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
GAA P10253 3/20 0.41
EDNRA P25101 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 2/20 0.39
HPGD P15428 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538438 0.93 KMT2A (0.56) KMT2AKDM4EALDH1A1L3MBTL1HSD11B1
SCHEMBL475089 0.89 ALDH1A1 (0.55) KMT2AKDM4EALDH1A1L3MBTL1HSD11B1
SCHEMBL29468592 0.89 ALDH1A1 (0.55) KMT2AKDM4EALDH1A1L3MBTL1HSD11B1
Biphenyl SCHEMBL11199366 0.88 KMT2A (0.49) KMT2AKDM4EALDH1A1MAPTKEAP1
SCHEMBL1423331 0.84 KDM4E (0.43) KMT2AKDM4EALDH1A1L3MBTL1HSD11B1
SCHEMBL22292321 0.84 GAA (0.55) KMT2AKDM4EALDH1A1L3MBTL1HSD11B1
SCHEMBL2487382 0.83 HTR6 (0.52) KMT2AKDM4EALDH1A1HSD11B1MAPT
SCHEMBL11225423 0.83 CA1 (0.52) KMT2AKDM4EALDH1A1EDNRAMEN1
SCHEMBL9683136 0.83 KMT2A (0.49) KMT2AKDM4EALDH1A1MAPTPOLB
SCHEMBL27623150 0.80 ALDH1A1 (0.49) KDM4EALDH1A1L3MBTL1HSD11B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323948-A Capacitor structures with improved electrical stress capability WESTINGHOUSE ELECTRIC CORP. (US) 1982-04-06 US claimed
US-3948788-A DIARYL SULFONES, HALOGEN-FREE AROMATIC COMPOUNDS MONSANTO COMPANY (US) 1976-04-06 US claimed
US-3948787-A DIARYL SULFONES, CARBOXYLIC ESTERS MONSANTO COMPANY (US) 1976-04-06 US claimed
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
US-20210122953-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALITY POLYMERS USA, LLC 2021-04-29 US disclosed
EP-3681933-A1 POLYMER-METAL JUNCTION Solvay Specialty Polymers USA, LLC (US) 2020-07-22 EP disclosed
WO-2019053164-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-03-21 WO disclosed
US-20180282483-A1 Polyarylene ether sulfone (PAES) Polymers and Methods for Making the Same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-10-04 US disclosed
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 US disclosed
CN-107207729-A Poly (arylene ether) ether sulfone (PAES) polymer and preparation method thereof 索尔维特殊聚合物美国有限责任公司 2017-09-26 CN disclosed
US-4824443-A HIGHLY POLAR SOLVENT BEND RESEARCH, INC. (US) 1989-04-25 US disclosed
EP-0273724-A2 Acid gas scrubbing by composite solvent-swollen membranes BEND RESEARCH, INC. (US) 1988-07-06 EP disclosed
US-4737166-A SEPARATION OF HYDROGEN SULFIDE AND CARBON DIOXIDE FROM HYDROGEN, CARBON MONOXIDE AND HYDROCARBON GASES; SUPPORTED POLYMER BEND RESEARCH, INC. (US) 1988-04-12 US disclosed
EP-0068695-A1 Blends of poly (parabanic acids) with other polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP disclosed
EP-0057104-A2 Polymers containing 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or sulfoxides EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-08-04 EP disclosed
US-4325860-A Polymers characterized by 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or aromatic sulfoxides EXXON RESEARCH & ENGINEERING CO. (US) 1982-04-20 US disclosed
US-4054937-A A BIPHENYL, DIPHENYLMETHANE, DIPHENYL OXIDE WESTINGHOUSE ELECTRIC CORPORATION (US) 1977-10-18 US disclosed
US-3948788-A DIARYL SULFONES, HALOGEN-FREE AROMATIC COMPOUNDS MONSANTO COMPANY (US) 1976-04-06 US disclosed
US-3948787-A DIARYL SULFONES, CARBOXYLIC ESTERS MONSANTO COMPANY (US) 1976-04-06 US disclosed