SCHEMBL14234875

SCHEMBL14234875

CN(C)CCN1CCc2ccc(O)cc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
ESR2 Q92731 3/20 0.63
LMNA P02545 2/20 0.63
MAPT P10636 2/20 0.63
KDM4E B2RXH2 1/20 0.63
PTK2B Q14289 1/20 0.63
DRD2 P14416 5/20 0.45
DRD1 P21728 5/20 0.45
DRD5 P21918 5/20 0.45
DRD3 P35462 5/20 0.45
NOS3 P29474 2/20 0.44
NOS1 P29475 2/20 0.44
NOS2 P35228 2/20 0.44
CHRM2 P08172 3/20 0.44
CHRM4 P08173 2/20 0.44
SIGMAR1 Q99720 1/20 0.43
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
CDK4 P11802 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4200884 0.82 ALDH1A1 (0.63) ALDH1A1ESR2LMNAMAPTKDM4E
SCHEMBL14235096 0.81 CHRM2 (0.48) ALDH1A1ESR2LMNAMAPTKDM4E
SCHEMBL27521564 0.79 KDM4E (0.56) ALDH1A1ESR2LMNAMAPTKDM4E
SCHEMBL93954 0.79 ESR1 (0.54) ALDH1A1ESR2DRD2DRD1DRD5
SCHEMBL7680979 0.78 ALDH1A1 (1.00) ALDH1A1ESR2LMNAMAPTKDM4E
Hydrochloric Acid SCHEMBL11030093 0.78 ESR1 (0.52) ESR2DRD2DRD1DRD5DRD3
SCHEMBL2462174 0.77 MAPT (0.57) ALDH1A1ESR2LMNAMAPTKDM4E
Fumaric Acid SCHEMBL7673702 0.75 LMNA (0.51) ALDH1A1ESR2LMNAMAPTKDM4E
SCHEMBL6717399 0.74 MAPT (0.51) MAPTKDM4EDRD2DRD1DRD5
SCHEMBL25818505 0.74 ALDH1A1 (0.65) ALDH1A1ESR2LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012163898-A1 DYE COMPOSITION USING A (HYDROXY)INDOLINE COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESS AND DEVICES L'OREAL (FR) 2012-12-06 WO disclosed