Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542239 | 0.93 | GPR119 (0.48) | GPR119TBK1IKBKENPBWR1MCHR1 | |
| SCHEMBL1550792 | 0.92 | GPR119 (0.47) | GPR119TBK1IKBKENPBWR1MCHR1 | |
| SCHEMBL2544987 | 0.90 | GPR119 (0.50) | GPR119TBK1IKBKENPBWR1MCHR1 | |
| SCHEMBL2542952 | 0.88 | GPR119 (0.48) | GPR119TBK1IKBKENPBWR1MCHR1 | |
| SCHEMBL14237487 | 0.88 | GPR119 (0.45) | GPR119NPBWR1MCHR1 | |
| SCHEMBL14237467 | 0.85 | GPR119 (0.51) | GPR119TBK1NPBWR1MCHR1 | |
| SCHEMBL1550872 | 0.83 | NPBWR1 (0.50) | GPR119NPBWR1MCHR1 | |
| SCHEMBL1549862 | 0.82 | GPR119 (0.43) | GPR119 | |
| SCHEMBL2536248 | 0.81 | GPR119 (0.44) | GPR119TBK1NPBWR1MCHR1 | |
| SCHEMBL14237663 | 0.81 | GPR119 (0.61) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |