Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 17/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1423306 | 0.99 | ACLY (0.45) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1423427 | 0.89 | HTR6 (0.35) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1422160 | 0.81 | ACLY (0.52) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1421917 | 0.80 | ALDH1A1 (0.47) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1422456 | 0.80 | ACLY (0.46) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1422682 | 0.78 | ACLY (0.46) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1590549 | 0.78 | HTR6 (0.47) | HTR6 | |
| Hydrochloric Acid SCHEMBL1590417 | 0.77 | HTR6 (0.46) | HTR6 | |
| SCHEMBL1423772 | 0.77 | ACLY (0.45) | ACLYHTR6ADRA2AHTR2CMET | |
| SCHEMBL1422004 | 0.76 | ACLY (0.46) | ACLYHTR6ADRA2AHTR2CMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297166-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-03-23 | — | — | EP | claimed |