Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 17/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422038 | 0.89 | POLB (0.35) | ACLYHTR6HTR2CADRA2ACCKBR | |
| SCHEMBL1422160 | 0.86 | ACLY (0.52) | ACLYHTR6HTR2CADRA2AMET | |
| SCHEMBL1421917 | 0.79 | ALDH1A1 (0.47) | ACLYHTR6HTR2CADRA2AMET | |
| SCHEMBL1590394 | 0.78 | HTR6 (0.46) | HTR6 | |
| SCHEMBL1423765 | 0.78 | ACLY (0.46) | ACLYHTR6HTR2CADRA2AMET | |
| SCHEMBL1422456 | 0.78 | ACLY (0.46) | ACLYHTR6HTR2CADRA2AMET | |
| Hydrochloric Acid SCHEMBL1423306 | 0.77 | ACLY (0.45) | ACLYHTR6HTR2CADRA2AMET | |
| SCHEMBL1423772 | 0.77 | ACLY (0.45) | ACLYHTR6HTR2CADRA2AMET | |
| SCHEMBL1422191 | 0.74 | ACLY (0.39) | ACLYHTR6ADRA2AMETCCKBR | |
| SCHEMBL1422004 | 0.74 | ACLY (0.46) | ACLYHTR6HTR2CADRA2AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297166-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-03-23 | — | — | EP | claimed |