Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SLC26A6 | Q9BXS9 | 4/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19814674 | 0.88 | ACKR3 (0.46) | PLATOPRK1KCNH2SLC26A6ACKR3 | |
| SCHEMBL29775777 | 0.88 | ACKR3 (0.46) | PLATOPRK1KCNH2SLC26A6ACKR3 | |
| SCHEMBL15471922 | 0.88 | OPRK1 (0.45) | SMN1; SMN2PLATOPRK1KCNH2SLC26A6 | |
| SCHEMBL14167749 | 0.83 | S1PR1 (0.42) | SMN1; SMN2PLATLMNAOPRK1KCNH2 | |
| SCHEMBL15464775 | 0.83 | PLAT (0.41) | PLATOPRK1KCNH2SLC26A6NPC1 | |
| SCHEMBL14240125 | 0.81 | NPC1 (0.45) | SMN1; SMN2CYP3A4MAOAKCNH2ACKR3 | |
| SCHEMBL893135 | 0.81 | S1PR1 (0.52) | PLATOPRK1KCNH2SLC26A6S1PR1 | |
| SCHEMBL14239264 | 0.78 | MAPT (0.43) | LMNACYP1A2CYP3A4MAOAPRKCZ | |
| SCHEMBL2300298 | 0.77 | LMNA (0.44) | SMN1; SMN2LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL26690781 | 0.77 | PTGES (0.43) | PLATLMNAOPRK1KCNH2SLC26A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168315-A1 | SUBSTITUTED PIPERIDINES AS GPR119 MODULATORS FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-13 | — | — | WO | disclosed |