SCHEMBL14239358 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	RAB9A	P51151	6/20	0.44

▸	NPC1	O15118	5/20	0.44

▸	LMNA	P02545	2/20	0.44

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	ALDH1A1	P00352	1/20	0.42

▸	CYP2C19	P33261	2/20	0.41

▸	CYP1A2	P05177	1/20	0.41

▸	CYP3A4	P08684	1/20	0.41

▸	L3MBTL1	Q9Y468	1/20	0.39

▸	MEN1	O00255	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	RXFP1	Q9HBX9	1/20	0.37

▸	GRM2	Q14416	1/20	0.37

▸	GRIN2B	Q13224	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14239050	0.92	RAB9A (0.40)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL6921870	0.91	RAB9A (0.40)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239051	0.90	RAB9A (0.40)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239132	0.89	ALDH1A1 (0.44)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239342	0.89	RAB9A (0.45)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239052	0.88	CYP11B2 (0.40)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239054	0.88	RAB9A (0.37)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239353	0.87	CYP3A4 (0.41)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239808	0.87	RAB9A (0.41)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1
SCHEMBL14239056	0.86	RAB9A (0.38)	RAB9ANPC1LMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012170845-A2	METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF	HEFFERNAN MICHELE L R (US)	2012-12-13	—	—	WO	disclosed