Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243736 | 1.00 | PIK3CD (0.32) | PIK3CDHSD17B10 | |
| SCHEMBL14243649 | 0.78 | — | — | |
| SCHEMBL14243650 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6588017 | 0.74 | GNAI3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6588013 | 0.74 | GNAI3 (0.33) | — | |
| SCHEMBL1602300 | 0.73 | TRPA1 (0.32) | — | |
| SCHEMBL3516783 | 0.73 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL1602298 | 0.73 | TRPA1 (0.32) | — | |
| SCHEMBL13223749 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL3281200 | 0.70 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927217-B1 | AMIDE COMPOUND AND PHARMACEUTICAL APPLICATION THEREFOR | JAPAN TOBACCO INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-2927217-B1 | AMIDE COMPOUND AND PHARMACEUTICAL APPLICATION THEREFOR | JAPAN TOBACCO INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| EP-2927217-A1 | Amide compound and pharmaceutical application therefor | Japan Tobacco Inc. (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-2927217-A1 | Amide compound and pharmaceutical application therefor | Japan Tobacco Inc. (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| WO-2014065413-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | 日本たばこ産業株式会社 (JP) | 2014-05-01 | — | — | WO | disclosed |
| EP-2719690-A1 | AMIDE COMPOUND AND PHARMACEUTICAL APPLICATION THEREFOR | Japan Tobacco Inc. (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-8604069-B2 | Amide compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PIK3CD 2576/4885HSD17B10 1207/4885 |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PIK3CD 2576/4885HSD17B10 1207/4885 |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PIK3CD 2576/4885HSD17B10 1207/4885 |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | PIK3CD 3148/4885HSD17B10 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.