SCHEMBL1424751

SCHEMBL1424751

O=C(c1ccccc1)n1ccnc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.47
FAAH O00519 1/20 0.47
MGLL Q99685 1/20 0.47
TBXAS1 P24557 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP24A1 Q07973 1/20 0.43
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HMOX2 P30519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9807751 0.90 CYP19A1 (0.46) CYP19A1FAAHMGLLTBXAS1CYP3A4
SCHEMBL9807759 0.87 KDM4E (0.45) CYP19A1FAAHMGLLTBXAS1MEN1
SCHEMBL18280916 0.87 ADH5 (0.54) CYP19A1TBXAS1MEN1KMT2ACYP3A4
Quinoline SCHEMBL27690684 0.85 ALDH1A1 (0.47) CYP19A1FAAHMGLLMEN1KMT2A
SCHEMBL13028408 0.85 ADH5 (0.51) CYP19A1CYP3A4MAPTTSHR
SCHEMBL799239 0.84 ALDH1A1 (0.52) TSHR
SCHEMBL28251856 0.83 CYP19A1 (0.41) CYP19A1FAAHMGLLCYP24A1CYP3A4
SCHEMBL30366356 0.82 FAAH (0.44) CYP19A1FAAHMGLLTBXAS1CYP24A1
SCHEMBL4808545 0.81 CYP19A1 (0.48) CYP19A1CYP24A1CYP3A4MAPT
SCHEMBL9879507 0.81 LSS (0.47) CYP19A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060354-A Magnetic quaternized ZIFs nano particles and modified ultrafiltration membrane thereof 吉林大学 2024-12-03 CN claimed
CN-115888413-B ZIFs particle loaded nanotube modified polymer-based ultrafiltration membrane, and preparation method and application thereof 吉林大学 2024-07-12 CN claimed
CN-117431583-A Organic ligand modified transition metal oxyhydroxide nano array electrode and preparation method and application thereof 中山大学 2024-01-23 CN claimed
CN-114561666-B Surface-modified metal organic frame nano array electrode and preparation method and application thereof 中山大学 2023-05-26 CN claimed
CN-115945212-A Low-temperature high-efficiency ammonia decomposition catalyst and preparation method thereof 大方元素(广东)科技有限公司 2023-04-11 CN claimed
CN-115888413-A ZIFs particle loaded nanotube modified polymer-based ultrafiltration membrane as well as preparation method and application thereof 吉林大学 2023-04-04 CN claimed
CN-114561666-A Surface-modified metal organic framework nano array electrode and preparation method and application thereof 中山大学 2022-05-31 CN claimed
CN-105732667-B The application of four core copper complexes and preparation method and catalysis tetrahydrofuran Gas-Phase Amination 常州大学 2017-11-10 CN claimed
CN-104130192-B Imidazolyl-benzaldehyde p-phenylenediamine bis-Schiff base and preparation method thereof 齐鲁工业大学 2017-05-24 CN claimed
US-8586481-B2 Chemical planarization of copper wafer polishing APPLIED MATERIALS, INC. (US) 2013-11-19 US claimed
EP-0974576-A2 Method of producing benzamide derivatives Mitsui Chemicals, Inc. (JP) 2000-01-26 EP claimed
EP-0894512-A1 Use of stabilised decontaminating compositions for the decontamination of toxic agents and/or pollutants Irdec S.A. (FR) 1999-02-03 EP claimed
EP-0606762-B1 Antibacterial resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-08-05 EP claimed
EP-0390558-B1 Aromatase inhibiting 4(5)-imidazoles ORION YHTYMAE OY (FI) 1994-09-07 EP claimed
EP-0606762-A2 Antibacterial resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-07-20 EP claimed
EP-0390558-A1 Aromatase inhibiting 4(5)-imidazoles ORION-YHTYMÀ„ OY (FI) 1990-10-03 EP claimed
US-4762636-A Process for the preparation of granules containing an active substance and to the use thereof as speckles for treating substrates CIBA-GEIGY CORPORATION (US) 1988-08-09 US claimed
EP-0236270-A2 Process for the production of articles containing an active agent, and their use as speckles CIBA-GEIGY AG (CH) 1987-09-09 EP claimed
EP-0076140-A2 1,3-Disubstituted imidazoles and a process for their production Kissei Pharmaceutical Co. Ltd. (JP) 1983-04-06 EP claimed
US-4240920-A A SURFACTANT, A PEROXY BLEACH AND A PORPHINE BLEACH THE PROCTER & GAMBLE COMPANY (US) 1980-12-23 US claimed