Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424751 | 0.84 | CYP19A1 (0.47) | TSHR | |
| SCHEMBL1640959 | 0.82 | ALDH1A1 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL9807759 | 0.82 | KDM4E (0.45) | ALDH1A1PKM | |
| SCHEMBL9807751 | 0.81 | CYP19A1 (0.46) | — | |
| SCHEMBL3273195 | 0.80 | HCAR2 (0.43) | ALDH1A1HCAR2TSHR | |
| SCHEMBL25507636 | 0.79 | CYP19A1 (0.54) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL1117958 | 0.79 | CYP19A1 (0.51) | ALDH1A1GAATSHRHDAC1HDAC6 | |
| SCHEMBL27566765 | 0.79 | ALDH1A1 (0.43) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL7077757 | 0.77 | CYP19A1 (0.38) | ALDH1A1 | |
| SCHEMBL28886442 | 0.77 | POLB (0.51) | ALDH1A1GAAHCAR2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702621-A | Preparation method of nikko rice | 海南聚和春企业管理合伙企业(有限合伙) | 2024-09-27 | — | — | CN | claimed |
| US-4166902-A | ESTERIFICATION OF SOLUBLE STARCH WITH NICOTINOYLIMIDAZOLE; SUSTAINED RELEASE BY SLOW HYDROLYSIS IN BIOLOGICAL ENVIRONMENT | FERRUTI PAOLO (IT) | 1979-09-04 | — | — | US | claimed |
| CN-118702621-A | Preparation method of nikko rice | 海南聚和春企业管理合伙企业(有限合伙) | 2024-09-27 | — | — | CN | disclosed |
| CN-118702621-A | Preparation method of nikko rice | 海南聚和春企业管理合伙企业(有限合伙) | 2024-09-27 | — | — | CN | disclosed |
| US-11834416-B2 | Cleavable agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230150943-A1 | CLEAVABLE AGENTS | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2023-05-18 | — | — | US | disclosed |
| US-20200172493-A1 | CLEAVABLE AGENTS | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2020-06-04 | — | — | US | disclosed |
| CN-105085390-B | A kind of preparation method of isoniazid | 浙江新赛科药业有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107827687-A | A kind of synthetic method of cold labeling chloramphenicol | 山东辉璟生物医药科技有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-105085390-A | Preparation method of isoniazid | ZHEJIANG SECOND PHARMA CO LTD | 2015-11-25 | — | — | CN | disclosed |
| EP-2658839-B1 | PROCESS FOR THE MANUFACTURE OF NICORANDIL | PROCOS SPA (IT) | 2014-10-22 | — | — | EP | disclosed |
| US-4596813-A | Pyridylcarbonyl and thiocarbonyl derivatives useful as fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| US-4588735-A | Fungicidal (trihalophenoxy or trihalophenthio) alkylaminoalkyl pyridines and pyrroles | CHEVRON RESEARCH COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4579856-A | Fungicidal N-pyridyloxyalkyl amides | CHEVRON RESEARCH COMPANY (US) | 1986-04-01 | — | — | US | disclosed |
| US-4544661-A | HORTICULTURE | CHEVRON RESEARCH COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| US-4532251-A | N-substituted-N',N'-disubstituted glycinamide fungicides | CHEVRON RESEARCH COMPANY (US) | 1985-07-30 | — | — | US | disclosed |
| US-4504484-A | Certain N,N-di-substituted-pyridine carboxamides, fungicidal compositions and fungicidal method of use | CHEVRON RESEARCH COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4169923-A | HIGH POLYMERS CONTAINING NICOTINIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE | FERRUTI PAOLO (IT) | 1979-10-02 | — | — | US | disclosed |
| US-4166902-A | ESTERIFICATION OF SOLUBLE STARCH WITH NICOTINOYLIMIDAZOLE; SUSTAINED RELEASE BY SLOW HYDROLYSIS IN BIOLOGICAL ENVIRONMENT | FERRUTI PAOLO (IT) | 1979-09-04 | — | — | US | disclosed |
| US-4067876-A | SUSTAINED RELEASE | FERRUTI PAOLO | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150943-A1 | CLEAVABLE AGENTS | LGMN, CTSL, GZMB | ALDH1A1 3728/4885APP 1339/4885GAA 86/4885 |
| US-20200172493-A1 | CLEAVABLE AGENTS | LGMN, CTSL, GZMB | ALDH1A1 3728/4885APP 1339/4885GAA 86/4885 |
| US-11834416-B2 | Cleavable agents | LGMN, CTSL, GZMB | ALDH1A1 3728/4885APP 1339/4885GAA 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.